Aging of the skin can be largely attributed to fibroblast dysfunctions and reduction of their biosynthetic activity. Regardless of the causes, aging fibroblasts begin to produce elements of the extracellular matrix in amounts insufficient to maintain a youthful appearance of the skin.
In recent years, more and more emphasis has been placed on mesotherapy as an anti-aging strategy. Mesotherapy is a medical procedure introduced by Pistor in 1958, based on intradermal injection of pharmacological substances such as nutrients, hormones, vitamins, enzymes and other reagents that have been diluted and administered directly to the treated region
The goal of mesotherapy is primarily to slow down and improve skin changes due to aging. The justification for developing complex mesotherapy preparations is based on the principle that aging skin needs to be supplied with various substrates that are essential for the proper functioning of fibroblasts.
A quintessential example are multi-constituent formulations containing vitamins, minerals, amino acids, nucleotides, coenzymes and antioxidants, as well as hyaluronic acid designed to help fibroblasts operate more efficiently, providing a more optimal environment for biochemical and energy production processes as well as counteracting the effects of oxidative stress.
What are peptides?
Peptides are organic chemical compounds that arise from the combination of two or more amino acid molecules linked by a peptide bond. Recent research shows that peptides identical to those produced by our bodies (biomimetic peptides) can be produced.
The peptides simulate the action of proteins in the skin. They are intelligent molecules because they are able to generate activation mechanisms involved in the synthesis of collagen and elastin fibers and are able to perform many biological effects on the skin that reverse the aging process.
Peptides are in many cases information relays, the presence of which determines the specific activity of cells, and if we already know the active biological peptides, we can divide them into relaxants, transporters and stimulants. There are many examples of peptides that are synthesized with the facial chain and are used in many mesotherapy products.
The effect of peptides on the skin:
The structural unit of nucleic acids are nucleotides consisting of three elements: a nitrogenous (purine-adenine, guanine or pyrimidine - cytosine, thymine, uracil), sugar (ribose or deoxyribose) and a phosphoric acid (V) attached to the sugar molecule. They are responsible for storing the genetic information of the organism and also mediate in the production of proteins. Thanks to understanding the structure of nucleic acids and understanding their participation in the life cycle of the cell, they gave the possibility of the emergence of new strategies in aesthetic medicine.
The basic principles of all cell processes contributing to the creation of nucleic acids:
Our appearance is determined by our DNA. Genes, and more specifically their activity, affect the appearance of the skin, its vulnerability to the aging process and perceived age, that is how others see us, despite our real age.
The effect of nucleotides on the skin:
Indications for the procedure: